Stream 3: Discovery Science #10
Tracks
Meeting Room 105 & 106
| Friday, August 21, 2026 |
| 2:00 PM - 3:30 PM |
| Meeting Room 105 & 106 (Level 1) |
Speaker
Ms Li Ern Yap
PhD Candidate
University of Sydney
Regulated mobilisation of a sequestered GLUT4 pool is selectively impaired in insulin resistance
2:50 PM - 3:05 PMBiography
Li Ern is a second-year PhD candidate in the David James Lab at The University of Sydney. Her research aims to uncover the molecular mechanisms that cause selective impairments in GLUT4 trafficking, a key process disrupted in insulin resistance.
Dr Simon Bond
Research Officer
The Baker Heart and Diabetes Institute
Chronic mtDNA damage drives muscle wasting through sustained integrated stress response activation and one-carbon metabolic rewiring
3:05 PM - 3:20 PMBiography
Dr Simon Bond is a cardiometabolic disease researcher investigating the molecular mechanisms underlying mitochondrial dysfunction and activation of the Integrated Stress Response. His work integrates novel pre-clinical models with mechanistic approaches to elucidate maladaptive stress signalling in cardiometabolic disease and identify potential therapeutic targets.
Simran Singh
Ph.d.
IIT Kanpur
Macrophage GPR18 signaling suppresses β-cell insulin secretion via a Gq-AMPK-sphingolipid pathway
3:20 PM - 3:35 PMBiography
Simran Singh is a PhD researcher in metabolic immunology studying macrophage–β-cell communication in obesity and diabetes. Their work focuses on GPCR signaling, lipid mediators, and immune regulation of pancreatic islet function to understand mechanisms underlying β-cell dysfunction in metabolic disease.