Our research focuses on how hormones modulate energy homeostasis. Our group has identified several hormones and is elucidating their molecular mechanisms in obesity, diabetes, cardiovascular disease, and cancer cachexia, using approaches spanning structural biology, biochemistry, molecular biology, physiology, and genetics.

Dr. Jonathan Long is an Associate Professor of Pathology and an Institute Scholar of Stanford ChEM-H (Chemistry, Engineering & Medicine for Human Health). His laboratory studies the molecular mechanisms of mammalian energy homeostasis. Dr. Long is the recipient of the Alfred P. Sloan Research Fellowship in Chemistry, the Breakthrough Sciences Award from the Ono Pharma Foundation, and the NIDDK Catalyst Award. Prior to arriving to Stanford, Dr. Long completed his Ph.D. in Chemistry at Scripps Research and his postdoctoral work at Harvard Medical School.

Professor Mark Febbraio is a National Health and Medical Research Council of Australia Investigator and the Head of the Cellular and Molecular Metabolism Laboratory at the Baker Heart & Diabetes Institute, Melbourne Australia. He is the Founder and Chief Scientist of Celesta Therapeutics and a Founder of Calmodulus Therapeutics. His research is focussed on understanding mechanisms associated with exercise, obesity, type 2 diabetes and cancer and his aim is to develop novel drugs to treat lifestyle related diseases. He has authored over >300 peer reviewed papers in leading journals and has >60,000 career citations. Throughout his career, he has won many prestigious awards including the Australian Physiological Society (AuPS) AK McIntyre Prize (1999), the Kellion Award for the Australian Diabetes Society (2017), The Eureka Scientific Prize (2020), The GSK Award for Research Excellence (2020), The Endocrinology Society UK International Medal (2021) the Kirsten and Freddy Johansen Rigshospitalet International Award, Denmark (2022), The AuPS Invited Lecture and Medal (2024) and the International Biochemistry of Exercise Honour Award (2026).

Dr Romana Stark is a neuroscientist at Monash University investigating neural mechanisms controlling food intake, glucose homeostasis and energy balance.