Inmunotek Industry Innovator -Is There More to Their Cough? How Phenotype and Endotype Mapping Personalises Asthma Care.
| Sunday, March 23, 2025 |
| 12:10 PM - 12:30 PM |
| Theatrette 2 |
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Sponsored By:
Inmunotek Australia
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Details
This session explores the evolving landscape of chronic cough phenotyping, the utility of FeNO in personalized management, and the challenges of translating these insights into clinical practice.
Chronic cough remains a complex and often refractory condition, necessitating a paradigm shift in classification and management. Traditionally categorized based on symptoms or etiology, emerging evidence supports the concept of treatable traits, particularly cough hypersensitivity and airway inflammation in adults.
T2 inflammation has been identified as a key treatable trait in chronic cough, with fractional exhaled nitric oxide (FeNO) serving as a valuable biomarker for phenotyping and guiding treatment decisions. Observational studies suggest that elevated FeNO levels can support the diagnosis of asthmatic cough.
Clinical evidence indicates that empirical inhaled corticosteroid (ICS) treatment provides modest therapeutic benefits, with greater efficacy in patients with elevated FeNO. Recent prospective studies have shown significant improvements in patient-reported outcomes following ICS therapy in FeNO-high chronic cough populations. Despite these advancements, knowledge gaps remain regarding FeNO’s optimal threshold levels, its role in repeated monitoring, and its integration into chronic cough clinical guidelines.
Speaker
Woo-Jung Song
University of Ulsan College of Medicine
Is There More to Their Cough? How Phenotype and Endotype Mapping Personalizes Asthma Care
12:10 PM - 12:30 PMBiography
Woo-Jung Song is a clinician, researcher, and Professor of Medicine in the Department of Allergy and Clinical Immunology at Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. His professional areas of interest include chronic cough and severe asthma. He is a member of guideline task forces for chronic cough, including the recent ERS and Korean Academy guidelines. Currently, he serves as the Chief Editor for ERJ Open Research, an associate editor for several specialty journals, a collaborator for the ERS NEUROCOUGH CRC, and a principal investigator in multi-center patient registry and clinical investigations for chronic cough in Korea.
