SLEEP AND BREATHING (symposium session): Digital biomarkers in sleep medicine and cardiology: CPAP - derived Cheyne-Stokes respiration as a medium for heart failure surveillance
Tracks
Track 5
| Saturday, November 14, 2026 |
| 3:45 PM - 5:15 PM |
Details
Cheyne-Stokes respiration (CSR) is a hallmark of haemodynamic instability and heart failure, yet its clinical utility has been largely confined to laboratory-based polysomnography. Emerging evidence demonstrates that modern CPAP devices can detect and longitudinally track CSR in the home setting. This creates a unique opportunity to transform routine CPAP therapy into a scalable cardiovascular monitoring platform.
This symposium will synthesise current evidence on CPAP-derived CSR (CPAP-CSR) as a digital biomarker for heart failure presence, progression, and exacerbation. Internationally relevant data from telemonitoring cohorts and waveform analyses will be discussed, alongside methodological considerations including algorithm variability and clinical implementation. Attendees will gain insight into how CPAP-derived ventilatory instability may function as an early-warning system for heart failure and how this technology could integrate into future surveillance frameworks.
Speaker
Prof Chin Moi Chow
Associate Professor
University of Sydney
Foundations: Ventilatory control instability and Cheyne-Stokes Respiratory (CSR) in heart failure
3:45 PM - 4:00 PMBiography
Associate Professor Chin Moi Chow is a researcher in sleep and integrative health whose work explores how sleep, circadian rhythms, physical activity, cardiopulmonary function, and metabolism interact to shape health and wellbeing. Taking a systems approach, she investigates how everyday behaviours and biological timing shape long-term health outcomes. Her research spans collaborations with academic and industry partners, translating scientific discoveries into practical innovations that support better sleep, healthier lifestyles, and improved wellbeing.
Mr Nashe Mutombe
Sleep Scientist
University of Sydney
Evidence: CPAP - derived CSR as a digital biomarker in heart failure - Systematic review synthesis
4:00 PM - 4:20 PMBiography
Nashe Marshall Mutombe is a clinical physiologist, researcher and Registered Polysomnographic Technologist (RPSGT) with postgraduate training in sleep at the University of Sydney. His clinical and research interests include cardiorespiratory sleep physiology, physiological signal analysis and digital biomarkers. His recent research has focused on CPAP-derived Cheyne–Stokes respiration and its potential application as a digital biomarker for heart failure surveillance.
Prof Matthew Naughton
Head Of General Respiratory & Sleep Medicine
Alfred Health
Clinical translation and implementation: CPAP-derived CSR in heart failure surveillance and management
4:20 PM - 4:45 PMBiography
Prof Matthew Naughton is head of general respiratory & sleep medicine at Alfred Hospital and is an adjunct clinical professor, Monash University. His interests include cardiopulmonary function in health and disease, during exercise, rest and sleep especially pertaining to the effects of positive airway pressure and oxygen therapy. He has been a lead clinician in a bariatric surgical RCT. He has been involved in the development of guidelines for the American Thoracic Society.
Dr Marcus McMahon
Sleep Disorders Physician
Epworth Healthcare
Chair
Biography
Prof Matthew Naughton
Head Of General Respiratory & Sleep Medicine
Alfred Health
Chair
Biography
