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ANZSSA PLENARY: (Plenary session) Sleep wake instability: Arousal systems and clinical perspectives

Tracks
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Track 5
Friday, October 10, 2025
9:00 AM - 10:30 AM
Hall L

Details

This session will present the latest knowledge and understanding about the brain systems and the neurophysiological mechanisms that regulate sleep-wake states, the systems responsible for arousal and awakenings from sleep, and how these mechanisms may explain features of clinical disorders of arousal. It will focus on the key nuclei of the ascending reticular arousal system i.e., orexin and noradrenaline, and how these systems interact to modulate sleep wake stability. It will answer the questions: How do the brain’s arousal systems control sleep functions? Can we refine how we detect and characterise arousals? How does sleep instability present clinically in insomnia, narcolepsy and hypersomnia, and how do we manage disorders of sleep and wake instability?


Speaker

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Prof Yuval Nir
Professor
Tel Aviv University

Sensory processing in sleep and systems mediating sensory-evoked awakenings

9:00 AM - 9:18 AM

Biography

Prof. Nir is a sleep investigator at Tel Aviv University and the Tel Aviv Sourasky Medical Center, Israel. He pursued direct M.Sc. in Computer Science through the TAU interdisciplinary Lautman program for outstanding students, proceeded to a Ph.D. in neurobiology at the Weizmann Institute (with Rafael Malach), and then to a postdoctoral fellowship with Prof. Giulio Tononi and Chiara Cirelli at the University of Wisconsin-Madison, training in sleep research. In 2012, Prof. Nir set up his own lab at Tel Aviv University. To date, Prof. Nir has published 57 articles, cited over 10,000 times to date. His research has been published in prestigious journals including Nature, Science, Nature Medicine, Nature Neuroscience, Nature Communications, Neuron, and he has won several awards and prizes for his research including a recent ERC grant on sleep and memory, the Sieratzki and Adelis prizes for neuroscience, as well as HFSP, EMBO, and Fulbright fellowships.
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Dr Rick Wassing
Postdoctoral Research Fellow
Woolcock Institute of Medical Research

To continue sleep or wake up: EEG spectral determinants of sleep instability in insomnia

9:18 AM - 9:36 AM

Biography

Rick Wassing is a sleep neuroscientist and an NHMRC Research Fellow at the Centre for Sleep and Chronobiology, Woolcock Institute, and the School of Psychological Sciences, Macquarie University. Dr Wassing's training included biochemistry (BSc) and neuroscience (MSc), and he obtained his Doctorate in May 2019 from The Netherlands Institute for Neuroscience, De Vrije Universiteit, Amsterdam, The Netherlands. His research focusses on the neurobiology of insomnia and links between insomnia and mental health.
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Dr Sheila Sivam
Sleep Physician
Woolcock Institute of Medical Research

REM Intruder: Sleep-wake instability in narcolepsy

9:36 AM - 9:54 AM

Biography

Dr. Sivam is a Respiratory and Sleep Specialist. After completing her medical training in Nova Scotia, Canada, she undertook further specialist training in Boston, Massachusetts and Pittsburgh, Pennsylvannia, USA. In Sydney, she completed her Respiratory and Sleep Medicine Fellowship requirements at Royal Prince Alfred Hospital and Woolcock Institute of Medical Research (WIMR). Dr. Sivam runs the Narcolepsy and Hypersomnolence Clinic at WIMR and is a member of the Australasian Sleep Association (ASA)Medicines Subcommittee, which is currently working on advocating for improved access to first line medications and research opportunities for narcolepsy and idiopathic hypersomnia. She is co-chair of the Sydney Health Partners Sleep Health Clinical Academic Group.
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Dr Tony Fernando
Psychiatrist, Sleep Specialist
Practice 92

Sleep-wake dissociations – manifestations and clinical management

9:54 AM - 10:12 AM

Biography

Dr. Tony Fernando is a New Zealand psychiatrist, sleep specialist, and educator. Trained in medicine and psychiatry, he completed a fellowship in sleep medicine at the University of Pennsylvania and a PhD on compassion in medicine. A former senior lecturer at the University of Auckland, he has received multiple teaching awards for his contributions to medical education. His clinical practice focuses on insomnia and parasomnias. Tony is also the author of the New Zealand bestseller Life Hacks from the Buddha, a book that blends psychology and Buddhist wisdom, informed by his work as a psychiatrist and former Buddhist monk.
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Mrs Nicole Verginis
Chief Clinical Scientist
Monash Children's Hospital

Chair

Biography

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Dr Andrea Ricciardiello
Postdoctoral Research Fellow
Woolcock Institute of Medical Research

Chair

Biography

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