Friday, October 10, 2025

9:00 AM - 10:30 AM

Hall L

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Overview

ANZSSA Plenary

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Details

This session will present the latest knowledge and understanding about the brain systems and the neurophysiological mechanisms that regulate sleep-wake states, the systems responsible for arousal and awakenings from sleep, and how these mechanisms may explain features of clinical disorders of arousal. It will focus on the key nuclei of the ascending reticular arousal system i.e., orexin and noradrenaline, and how these systems interact to modulate sleep wake stability. It will answer the questions: How do the brain’s arousal systems control sleep functions? Can we refine how we detect and characterise arousals? How does sleep instability present clinically in insomnia, narcolepsy and hypersomnia, and how do we manage disorders of sleep and wake instability?