Dr Michela Noseda leads a team of research at Imperial College London, studying heart failure to develop novel patients stratification and precision medicine approaches. She obtained her MD (Universita' Cattolica del sacro Cuore, Rome) and subsequently a PhD. Michela worked across the US (Albert Einstein College of Medicine and Baylor College of Medicine) and Canada (University of British Columbia) and is now an academic at the National Heart and Lung Institute. She uses genomics and computational approaches to study the cellular and molecular landscape of the human heart and drivers of adverse cardiac remodeling and, develops cardiac disease modelling based on human iPS-derived cells. She co-leads highly interdisciplinary projects and international consortia promoting team-science to accelerate discovery. She is an experienced public engagement advocate communicating how research will advance insights into heart disease that may ultimately alleviate the need for transplantation.

Dr Corey Giles is Head of the Systems Medicine and Bioinformatics laboratory at the Baker Heart and Diabetes Institute. He leads a program of research focused on understanding the mechanisms through which genetics and metabolism affect cardiovascular disease. By integrating biobank-scale data with advanced bioinformatics, his team is unravelling the molecular architecture underlying heart conditions. This systems-level approach is driving precise early diagnosis, risk assessment, and the development of targeted therapies.

Professor Mirana Ramialison is Group Leader of the Transcriptomics and Bioinformatics Laboratory at the Murdoch Children’s Research Institute in Melbourne, and co-Director of the reNEW Bioinformatics Hub of the Novo Nordisk Foundation for Stem Cell Medicine. Prof Ramialison received her Engineering degree from the University of Luminy in France, after which she worked as a programmer at the ERATO differentiation project in Kyoto. She obtained her PhD from the European Molecular Biology Laboratory in Heidelberg in 2007 and joined the Victor Chang Cardiac Research Institute in Sydney as an EMBO and HFSP Post-Doctoral Fellow in 2010. As an NHMRC/Heart Foundation Career Development Fellow, she established her first laboratory at the Australian Regenerative Medicine Institute (Monash University) in 2014. She is currently a Heart Foundation Future Leader Fellow. Prof Ramialison has delivered algorithms that enable the generation of new knowledge in our understanding of embryonic development and she is pioneering the field of spatial transcriptomics, having published the first 3D transcriptome map of the mammalian heart and the first visualisation of spatially-resolved transcriptome data in immersive environments. ramialison-lab.github.io/