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Mechanisms and Preclinical Discovery: New therapeutic targets and treatments for CVD

Tracks
Track 3
Sunday, August 9, 2026
9:00 AM - 10:30 AM

Speaker

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Assoc Prof Shiang Lim
Principal Research Fellow
St Vincent's Institute of Medical Research

Remote stem cell therapy for cardiac repair: Translating discovery from bench to bedside

9:00 AM - 9:20 AM

Biography

Associate Professor Lim is a Principal Research Fellow and Head of the Cardiac Regeneration group at St Vincent’s Institute of Medical Research (SVI) in Australia. He currently serves as a Council member of the ISHR (Australasian section), and is an active member of both the Australasian Society for Stem Cell Research (ASSCR) and the Australian Cardiovascular Alliance. Lim earned his PhD from University of Strathclyde (UK) in 2005 and completed a four-year post-doctoral fellowship at The Hatter Cardiovascular Institute, University College London. Lim joined the then O’Brien Institute in 2010, which later merged with SVI in 2015. As a translational research scientist, his work focuses on cardiometabolic diseases. His multidisciplinary research programme integrates stem cell biology, bioengineering, and pharmacology to develop innovative and translatable therapies for cardiometabolic diseases.
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Prof Livia Hool
Wesfarmers, UWA-VCCRI Chair In Cardiovascular Research
University of Western Australia

Mitochondrial-based therapies

9:20 AM - 9:40 AM

Biography

Professor Livia Hool is the Wesfarmers, UWA-VCCRI Chair in Cardiovascular Research and Director, Ben Beale Laboratory in Cardiovascular Research at The University of Western Australia. She is currently President of the Australian Physiological Society. She serves on several international committees including the American Heart Association BCVS Leadership Committee and BCVS Katz Award Committee. She is currently Treasurer of International Society for Heart Research (ISHR) World Council (2022-25; re-elected 2025-28) and past President ISHR Australasian section (2013-16; re-elected 2016-19). Her research focuses on the role of the L-type calcium channel in the excitability of the heart and in the regulation of energetics, with an emphasis on designing therapy to prevent the development of cardiomyopathy and heart failure.
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Prof Enzo Porrello
Theme Director, Stem Cell Biology
Murdoch Children's Research Institute

Cardiac patches in large animal models

9:40 AM - 10:00 AM

Biography

Professor Enzo Porrello FISHR FAHMS is Director of Stem Cell Medicine, founding Co-Director of the Melbourne Centre for Cardiovascular Genomics and Regenerative Medicine, Node Director of the Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW) and Head of the Heart Regeneration Group at the Murdoch Children’s Research Institute (since 2017). He previously held appointments as founding Co-Director of the UQ Centre for Cardiac and Vascular Biology and Head of the Heart Regeneration Group at The University of Queensland (2012-2017). Over the course of his career, Prof Porrello has made important contributions to our understanding of mammalian heart regeneration and has pioneered the development of human cardiac organoids for drug discovery. Prof Porrello’s research has been recognised by numerous awards. He is an elected Fellow of the International Society for Heart Research and the Australian Academy of Health and Medical Sciences. Prof Porrello is also a biotech founder - his companies Dynomics and Ibnova Therapeutics are developing new treatments for heart failure based on breakthrough stem cell technologies developed by his group.
Dr Yen Chin Koay
Postdoctoral Researcher
Heart Research Institute

NAD+ therapy for HFpEF

10:00 AM - 10:15 AM

Biography

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