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Genetics Prize session

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Friday, August 2, 2024
10:45 AM - 12:15 PM
Meeting Room 8

Speaker

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Dr Costas O'Mahony
Nuffield Health at St Bartholomew's Hospital

Risk stratification in HCM: The past, present and future

10:45 AM - 11:15 AM

Biography

Dr Costas O’Mahony is a consultant cardiologist based at the Centre for Inherited Cardiovascular Disease Unit at St Bartholomew’s Hospital in London UK and leads the alcohol septal ablation programme. He studied medicine at Imperial College London and graduated with a first-class BSc(Hons) in immunology in 1998 and with distinction in medicine in 2001. He is a fellow of the Royal College of Physicians. Dr O’Mahony was awarded an MD(Res) by University College London for research in sudden cardiac death in hypertrophic cardiomyopathy. He contributed to the 2014 ESC guidelines on the diagnosis and management of hypertrophic cardiomyopathy and led the development and validation of a risk prediction model for sudden cardiac death in HCM (HCM Risk-SCD). He is an honorary associate professor at the Institute of Cardiovascular Science at University College London and his current research is focused on clinical outcomes in cardiomyopathies and stereotactic radiotherapy for the treatment of symptomatic left ventricular outflow tract obstruction. Dr O’Mahony runs a specialist cardiomyopathy clinic and performs invasive haemodynamic assessments, cardiac biopsies, alcohol septal ablation and percutaneous coronary intervention.
Mr Luke Spencer
Phd Candidate
St Vincent's Institute

Genetic and Echocardiographic Determinants of Atrial Fibrillation in Athletes

11:15 AM - 11:30 AM

Biography

Luke is a 2nd year PhD student at the University of Melbourne, researching exercise induced cardiac filling in the Heart, Exercise and Research Trials Lab at St Vincent's hospital Melbourne.
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Dr Natasha Gorrie
Phd Candidate, Cardiologist
Victor Chang Cardiac Research Institute

Investigating the Role of Genes and the Environment in Heart Failure with Preserved Ejection Fraction

11:30 AM - 11:45 AM

Biography

Dr Natasha Gorrie is a PhD Candidate and Cardiologist at the Victor Chang Cardiac Research Institute and UNSW. She completed training at St Vincent’s Hospital Sydney, with a focus on advanced heart failure and transplantation. She finished a clinical and research fellowship in infiltrative cardiomyopathies and heart failure at St Vincent’s and the Victor Chang Cardiac Research Institute in 2022. Her PhD on HFpEF and cardiac amyloidosis focusses on genetics, early diagnostic techniques and atrial myopathy and is supported by a NHMRC scholarship. Dr Gorrie maintains an academic focus with academic appointments at the University of New South Wales and University of Notre Dame as a Conjoint Lecturer.
Dr Kelly Martinovich
Research Fellow
Murdoch University

The Development of Novel tailored Therapeutics for Familial Hypercholesterolemia

11:45 AM - 12:00 PM

Biography

Dr Kelly Martinovich is a Scientific Research Fellow who is passionate about bring novel therapeutics to the market. Kelly was awarded her PhD in 2021 by the University of Western Australia for proof-of-concept work developing novel antisense compounds for people with rare variants of Cystic Fibrosis. Kelly now works as part of the Molecular Therapy Lab that is developing novel therapeutics for people with genetic conditions. In 2022 Kelly was an inaugural recipient of an Western Australian Future Health & Innovation Fund’s, Innovation Fellowship to establish a potency assay for a novel drug delivered via nasal spray. Kelly works closely with the community and enjoys having consumers embedded in her research.
Dr Ashwin Bhaskaran
EP Fellow
Westmead Hospital

The impact of spatial distribution of likely pathogenic/pathogenic variants on clinical outcomes in LMNA cardiomyopathy – An international, multi-centre registry-based study

12:00 PM - 12:15 PM

Biography

Ashwin is an electrophysiology fellow at Westmead Hospital and PhD candidate with the Westmead Applied Research Centre, University of Sydney. His research is supported by the NHMRC Postgraduate Research Scholarship and focuses on refinement of risk stratification processes for sudden cardiac death in heart disease.
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Prof Diane Fatkin
Faculty
Victor Chang Cardiac Research Institute

Chairperson

Biography

Professor Diane Fatkin trained in Clinical Cardiology and Molecular Genetics and is currently Head of the Sr Bernice Research Program in Inherited Heart Diseases, in the Molecular Cardiology Division of the Victor Chang Cardiac Research Institute, Sydney. She also holds appointments as Honorary Medical Officer in the Cardiology Department, St Vincent’s Hospital, and Professor (conjoint) in the Faculty of Medicine, UNSW Sydney. Her research is focused on understanding the molecular genetic basis of inherited cardiomyopathies, with a specific interest in familial dilated cardiomyopathy and familial atrial fibrillation. This work spans from clinical and genetics studies in families with inherited cardiomyopathies, to functional genomics in cell, mouse, and zebrafish models. A major objective of the team’s research is “bench-to-bedside” translation of new insights about disease mechanisms into personalised approaches to patient management.
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Dr Vimal Patel
Consultant Cardiologist
Fiona Stanley Hospital

Chairperson

Biography

Dr Patel is a Consultant Cardiologist at Fiona Stanley Hospital and Royal Perth Hospital, Western Australia. Dr Patel undertook a clinical research fellowship at The Heart Hospital, UCL where he obtained his MD (Res) for research on myocardial fibrosis in hypertrophic cardiomyopathy. He has maintained a clinical interest in managing patients with inherited heart muscle disease. Additional clinical interest include managing patients with advanced heart failure and implantation of cardiac devices. He continues to maintain research interest in the field of inherited heart muscle disease.
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