ADS Discovery Science Targeting Metabolic Stress in Diabetes: From Mitochondria to Multiorgan Outcomes

Tracks
Breakout 2: Room 6
Friday, August 22, 2025
8:30 AM - 10:30 AM
Room 6

Speaker

Ms Qian Wang
Student
RMIT University

Effect of carnosine on cognitive function in Type 2 diabetes mellitus-induced cognitive impairment in mice

8:30 AM - 8:45 AM

Abstract

Biography

Qian is a fourth-year PhD student from RMIT University. She is passionate about understanding the complex relationship between diet, health, and brain function. Her research focuses on how Type 2 diabetes affects cognitive abilities like memory and thinking, and explores potential treatments to help improve these functions.
Dr Alexis Diaz Vegas
Postdoctoral Fellow
University of Sydney

Uncoupling mitochondrial dysfunction from insulin resistance: Ceramide as a metabolic gatekeeper

8:45 AM - 9:00 AM

Abstract

Biography

Alexis is a Research Fellow at the Charles Perkins Centre, University of Sydney, investigating how mitochondria and lipids regulate metabolism and insulin resistance. Over the past four years, he has developed novel techniques to study insulin sensitivity and explored the interplay between ceramides and mitochondria in skeletal muscle.
Ms Carys Campbell
Research Assistant
The University of Sydney

Tirzepatide reduces liver steatosis in a murine model of insulin-deficient diabetes and obesity

9:00 AM - 9:15 AM

Abstract

Biography

Carys Campbell graduated from the UTS in 2022 with a Bachelor of Medical Science and completed an Honours (Class I) project with UNSW from 2023-2024. Carys currently works as a research assistant with the University of Sydney, and her work focusses on pregnancy, obesity and diabetes.
Mrs Cassandra Robertson
Cde/apd
Griffith University

Semaglutide provides superior cardioprotection compared to pravastatin and offsets pravastatin-induced cardiac impairment in obesity

9:15 AM - 9:30 AM

Abstract

Biography

Cassandra Robertson is an Accredited Practising Dietitian and Credentialed Diabetes Educator at Macintyre Health. She is presenting findings from her Master of Medical Research through Griffith University, which explored the cardioprotective effects of semaglutide versus pravastatin in an ischaemia-reperfusion injury model. Cassandra integrates clinical expertise with translational research in metabolic health.
Dr Matilda Longfield
Postdoctoral Researcher
Kolling Institute

Liraglutide improves cardiac outcomes in a pre-pregnancy mouse model

9:30 AM - 9:45 AM

Abstract

Biography

Dr. Longfield is a postdoctoral researcher working in A/Prof. Glastras' team at the Kolling institute. Her research focuses on adverse outcome prediction in the context of diabetes, obesity and pregnancy. Dr. Longfield's work spans both clinical and basic science research with a strong focus on diabetes-related translational medicine.
Assoc Prof Darren Henstridge
Lecturer / Researcher
University of Tasmania

Overexpression of ACAD10 alters the insulin signaling pathway and activates aspects of the mitochondrial integrated stress response (ISRmt).

9:45 AM - 10:00 AM

Abstract

Biography

Darren is an Associate Professor in Health and Human Performance at UTAS. His research focuses on using pre-clinical models of insulin resistance, diabetes and obesity to study metabolic phenotypes, pathways and processes. His research is focused on understanding mitochondrial and whole-body metabolic dysfunction and identifying targets to treat these conditions.
Assoc Prof Carsten Schmitz-Peiffer
Principal Research Fellow
University of Sydney

Effects of muscle-specific protein kinase C epsilon deletion, caloric dilution and gender on glucose homeostasis in fat-fed mice

10:00 AM - 10:15 AM

Abstract

Biography

Carsten Schmitz-Peiffer investigates the mechanisms by which lipid oversupply interferes with insulin action, focussing on the role of protein kinase C. He recently moved to the University of Sydney, where he is investigating the potential targeting of protein kinase C for the treatment of type 2 diabetes
Dr Jay Jha
Researcher
Department of Diabetes / School of Translational Medicine / Monash University

Nox5 deletion confers renal protection in a rabbit model of diabetic kidney disease

10:15 AM - 10:30 AM

Abstract

Biography

As a renal scientist, Dr. Jha contributions to diabetes and kidney disease research are exceptional. Beginning with his PhD, where he identified the NOX pathway and translated his findings into clinical studies, he continues to lead projects aimed at discovering novel therapeutic targets and biomarkers for diabetes and kidney disease.
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Assoc Prof Kathryn Aston-Mourney
Academic
Deakin University

Chairperson

Biography

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Dr Lewin Small
Research Fellow
The University of Sydney

Chairperson

Biography

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