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ADS Basic Science Orals 1: Diabetes Complications and Metabolism

Tracks
Stream 3
Wednesday, August 23, 2023
1:30 PM - 3:30 PM
Room E2

Speaker

Ms Misbah Aziz
PhD Student
Monash University

Epigenetic regulator histone methyltransferase EZH2, as a novel target in endothelial to mesenchymal transition in diabetes associated cardiovascular complications

1:30 PM - 1:45 PM

Abstract

Biography

Misbah Aziz is a Ph.D. student in the second year of her degree at the department of diabetes, Monash University. Melbourne. Her research interest is about the epigenetics basis of diabetic-associated cardiovascular disease.
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Dr Sara Litwak
Research Officer
St Vincent's Institute of Medical Research

Single cell transcriptomics analysis reveals a BIM-mediated stress signature in beta cells in a mouse model of type 2 diabetes

1:45 PM - 2:00 PM

Abstract

Biography

Dr Litwak has been involved in the study of leptin resistance and obesity since 2011, first at Monash University and since 2014 at St Vincent's Institute for Medical Research. She is interested in the molecular mechanisms contributing to Insulin Resistance and beta cell failure in models of obesity and T2D.
Dr Jay Jha
Research Fellow
Central Clinical School / Monash University

NOX5: a potential therapeutic target and a biomarker of diabetic kidney disease

2:00 PM - 2:15 PM

Abstract

Biography

Dr. Jha is a previous JDRF/NHMRC funded early-mid career research fellow. The leadership and significance of his research impact is reflected by translation of his preclinical work in DKD to clinical trials as well as by his highly cited publications (>2400 cites) in the leading journals of diabetes and nephrology.
Dr Abdul Waheed Khan
Research Fellow
Monash University

Transcriptomic regulation during endothelial to mesenchymal transition (EndMT) in diabetes associated vascular complications

2:15 PM - 2:30 PM

Abstract

Biography

Dr. Abdul Waheed Khan is a previous Heart Foundation postdoctoral fellow and an early-mid career Research Fellow at the Department of Diabetes, Monash University. Research interests includes cardiovascular complicating of diabetes.
Dr Kim Loh
Laboratory Head
St Vincent's Institute of Medical Research

Salt-Inducible Kinase 3 (SIK3): A Novel Regulator of Energy Homeostasis

2:30 PM - 2:45 PM

Abstract

Biography

Dr Loh is the head of the Diabetes and Metabolic Disease Laboratory at St Vincent's Institute. He was awarded an ADS Skip Martin ECR Fellowship in 2018. His long-term research interests involve the development of a comprehensive understanding of key regulatory pathways in beta-cell function, glucose and energy metabolism.
Dr Jantina Manning
Research Fellow
Centre for Cancer Biology / University of South Australia

Nedd4L as a new regulator of diabetic nephropathy

2:45 PM - 3:00 PM

Abstract

Biography

Jantina Manning is a mid-career research fellow in the Centre for Cancer Biology, Adelaide, Australia. She leads a research project focused on how the regulation of proteins by ubiquitination (particularly by the ubiquitin ligase Nedd4-2) protects against chronic kidney disease and diabetic nephropathy.
Dr Stewart Masson
Postdoctoral Researcher
University of Sydney

Genetic variance at the defensin locus contributes to insulin sensitivity via microbiome composition

3:00 PM - 3:15 PM

Abstract

Biography

Stewart is a postdoctoral researcher in David James' lab at the University of Sydney's Charles Perkins Centre. After completing a PhD in cell signalling and glucose transport in New Zealand, Stewart moved to Sydney in 2021. Currently, Stewart studies insulin resistance via systems biology and diversity outbred mice.
Dr Mitchell Sullivan
Senior Lecturer
Mater Research

Youth with type 1 diabetes at higher risk of developing diabetic kidney disease have alterations in their urine and plasma metabolomic and mitochondrial DNA profiles.

3:15 PM - 3:30 PM

Abstract

Biography

Dr. Mitchell Sullivan studies glycogen's role in metabolic diseases like diabetes. He explores glycogen structure and function, revealing the fragility of diabetic liver glycogen. He investigates glycogen's involvement in nervous system disorders, such as Lafora Disease, and currently examines the connection between diabetes, mitochondrial dysfunction and kidney disease.

Chairperson

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Magdalene Montgomery
Scientist
University of Melbourne

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Andrew Murphy
Laboratory Head
Baker Heart and Diabetes Institute

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